The iFishIENCi EU funded project is bringing together 16 partners in a trans-disciplinary effort towards making genuine improvements to fish farming worldwide. Fish aquaculture is essential for providing healthy food to a growing world population, but its success depends upon our ability to find more sustainable farming practices. This means more effective ways of monitoring fish-health and welfare, as well as more efficient ways of feeding fish that reduce pressure upon the source of fish-feed ingredients, such as agricultural crops and wild-caught fish for fishmeal and oil. iFishIENCi iBOSS technology is being designed to significantly advance these required achievements. Through providing accurate, real-time data, iBOSS will enable producers to quickly make robust decisions from a holistic, integrated management approach. New iFishiENCi feed formulations will help maintain quality fish growth, using ingredients made from recycled, organic resources, reducing dependency on protein from wild-caught fish. Using advanced digital information technology, the iFishiENCi project is developing a Biology Online Steering System (iBOSS), which will monitor all aspects of fish and their environment critical for healthy, sustainable farmed fish. This cutting-edge research will produce innovative, breakthrough intelligent feeding technologies to support ambitious, but sustainable growth for the European aquaculture industry: Fish-Talk-To-Me: a product enabling continuous monitoring and control of fish behaviour, health, physiology and welfare. Fish-Talk-to-Me integrates a set of technologies and data processing systems for integration with online monitoring systems. Fish-Talk-to-Me encompasses fish tagging technology for continuous gathering of fish physiological data, camera technology for automatic assessment of fish behaviour, echo-sounders, and a digital twin of fish digestion efficiency (FishMet). iBOSS: using advanced digital information technology, the iFishiENCi project is developing a flexible open Biology Online Steering System (iBOSS), which will monitor all aspects of fish and their environment critical for healthy, sustainable farmed fish. It will maximise feed utilization and minimise environmental impacts through Smart Feeding. Smart RAS: development of a unique European research, innovation and piloting capacity, based on Recirculating Aquaculture Systems. It will be fully equipped with iBOSS technology and exploited at the global aquaculture market level. Waste2Value: A set of validated value chain processes for optimal valorisation of waste and sludge from different aquaculture production systems, and accounting for the fish species and feed products.